THE MALIGNANT EFFECTS OF FERTILITY DRUG AND ITS BIRTH DEFECTS

Fertility drugs are those drugs that an individual take to get fertile in the reproductive system. The use of fertility drugs is more associated than the female than the men. This is because the fertility drug is used to encourage the follicle of the female reproductive system. The place where the drug functions the most in the female body is in the ovary section of the female reproductive system. The fertility drugs are mostly used for couples who are infertile. This is mostly the case of infertile women. The drug can be grouped into two and they are the Gonadotropin hormone releasing fertility drug and the Oestrogen antagonists fertility drug. The gonadotropin-releasing hormone fertility drug can also be called a gonadotropin-releasing hormone agonists.

The gonadotropin stimulates or encourages the release of gonadotropins from the frontal pituitary gland in the human body. Gonadotropins are the hormones in the human body that usually encourages the gonads (testes) in man and the female reproductive ovaries to be fertile. These glands can be extracted from the man or the woman, through the urine or through the use of genetic modification. The menotropin which can also be called a human menopausal gonadotropin (HMG) is a hormonally lively medication which assists in the treatment of the human fertility issues.

Constantly the plural is needful and used as the medicine is combined with gonadotropin. Just like the Medicine Direct gonadotropin, the menotropin is extracted from the urinal analysis of women who have experienced their menopause. The Oestrogen antagonists are those fertility drugs that are capable of constraining the effects of estrogen in the female reproductive system. The two main types of Oestrogen inhibitors are the Clomiphene and the Aromatase inhibitors.

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The Clomiphene inhibitors are those inhibitors in the human body mostly in the female body that are estrogen selective receptor modulator, which is capable of being used as a fertility drug. It functions better as an ovarian stimulator and it works by restraining the harmful message of the estrogen in the brain center of the hypothalamus section. After, making the harmful messages of the estrogen reaching the hypothalamus of the brain restrained, the hypothalamus then releases gonadotropin-releasing hormone (GnRH) which then in its turn encourages the frontal anterior pituitary gland to secrete an LH and an FSH which assists in the ovulation.

The Aromatase inhibitors, which is foremost used in the treatment of breast cancer issues can also function as a fertility medicine, the method which it uses to function is somewhat similar to the method used by the clomiphene. The Aromatase inhibitor works best when used in postmenopausal women who are suffering from breast cancer and it is also, used in men who are suffering from gynecomastia.

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Feb 28, 2017

The aromatase acts an enzyme drug that integrates estrogen in the female body. It is a well-known scientific fact that estrogen is needful for the breast to grow and also, ovarian cancers need estrogen to multiply its infected cells as well. Thus the Aromatase inhibitors are taken to obstruct the body system from producing estrogen and it can as well obstruct the operation of the estrogen on the receptors of the brain.
Aside from the usefulness and the austerity employed in carrying out its programmed duties in the human body. It must be noted that the use of fertility drugs has its own side effects in the body of the patient, and just like every other hormone stimulating drug, these drugs are to be used in moderation or are to be totally avoided if not needful for the body.

Hormone stimulating drug
Feb 28, 2017

The Gonadotropins and the Oestrogen antagonists have an elemental side effect of stimulating more than many follicles and many other ovarian hormones leading to many or multiple births and in some cases, the situation of having an ovarian hyperstimulation syndrome is a possibility. The clomiphene just like the gonadotropin and the Oestrogen antagonist is capable of having adverse effects on the body if used for long. The clomiphene has been recorded to have an adverse side effect of a reversible ovarian dilation. Other side effects made on the drug include visual symptoms of blurred or faded vision, having a double vision, floaters, sensitivity of the eyes to light, headaches, and migraines, vasomotor flushes also known as hot flashes.

Oestrogen antagonist
Feb 28, 2017

Light sensitivity and pupil contraction, abnormal uterine bleeding and in some cases abdominal discomfort. A more serious side effect associated with the drug include a high blood level of triglycerides, an inflammation of the liver, reversible baldness, and ovarian hyperstimulation syndrome. The clomiphene has also been recorded to cause multiple ovulation, this can lead to the birth of twins and sometimes for some other people it can lead to the birth of triplets. Another recorded case of the using the drug for a long period of time especially in a year could result in the development of ovarian cancer, this is mostly the case in the female body. But, the feat can only be possible in females who had never been pregnant and are infertile.

Osteoporosis for patients

Another given case of the adverse side effects of the clomiphene is the occurrence of the fetal and newborn anomalies for patients who use clomiphene. The aromatase inhibitors, on the other hand, do have its own side effects and this is just like any other drug which poses a threat to the body when used for long. The side effects of using aromatase inhibitors include a high tendency of the patient developing a joint disorder and osteoporosis. The joint disorders include having a series of joint pain, arthritis, arthrosis and other joint syndromes.

 


Osteoporosis of the jaw is a serious side effect associated with using the fertility drug as well and research has proven that when Bisphosphonates is added to the medication, the osteoporosis is likely to not happen to the patient. Also, if Statin another kind of inhibitor is mixed to the aromatase inhibitor, it is capable of reducing the risk associated with osteoporosis for patients. A come serious side effects associated with using the aromatase inhibitor are a reduction in the growth of bones, aggressive behavior, liver dysfunction, adrenal insufficiency, kidney failure and many other risks.